Find Studio

Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry which is an analytical technique that measures the mass-to-charge ratio of charged particles.

pFind Studio is a computational solution for such mass spectrometry-based proteomics. It germinated in 2002 in Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China. We call ourselves "pFinders". Our goal is to study bioinformatics algorithms and to develop easy-to-use software tools to help answer biological questions.

What's New

Oct 29, 2022 - Our paper A universal database reduction method based on the sequence tag strategy to facilitate large-scale database search in proteomics has been published on International Journal of Mass Spectrometry.


Oct 13, 2022 - Master Student Wu Yu-zhuo visited NIBS and communicated.


Sep 24, 2022 - pFinders visited the Fragrant Hills Park (香山公园) together.

Software

pFind is a search engine for peptide and protein identification via tandem mass spectrometry. [download...]




pLink is a tool dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry.
[download...]




pNovo+ is a de novo peptide sequencing algorithm using complementary HCD and ETD tandem mass spectra. [download...]

Benchmark

We participated in the ABRF iPRG study with pFind developed by our group in the past few years.



"The mission of the ABRF iPRG (formerly the Bioinformatics Committee) is to educate ABRF members and the scientific community on best application and practice of bioinformatics toward accurate and comprehensive analysis of proteomics data."


We believe it is advantageous to improve our algorithms, software tools and strategies for proteome informatics.